https://doi.org/10.1140/epjd/e2015-60204-7
Regular Article
Ion induced fragmentation cross-sections of DNA constituents*
Physikalisch-Technische Bundesanstalt,
Bundesallee 100, 38116
Braunschweig
a
e-mail: benedikt.rudek@ptb.de
Received: 30 March 2015
Received in final form: 13 July 2015
Published online: 27 October 2015
Proton collision with chemical analogs for the base, the sugar and the phosphor residue of the DNA, namely pyrimidine, tetrahydrofuran and trimethyl phosphate, respectively, has been investigated. The impact energies ranged from 300 keV up to 16 MeV. For the first time, relative fragmentation cross-sections for proton impact are reported for tetrahydrofuran and trimethyl phosphate; previously reported cross sections for pyrimidine are extended for energies beyond 2500 keV. Ionization of tetrahydrofuran leads to a ring break in about 80% of all events, trimethyl phosphate predominantly fragments by bond cleavage to one of the three methyl-groups and for pyrimidine the parent ion has the highest abundance. Such comparison supports earlier findings that the sugar is the weak spot for strand breaks.
© The Author(s) 2015. This article is published with open access at Springerlink.com
Open Access This is an open access article distributed
under the terms of the Creative Commons Attribution
License (http://creativecommons.org/licenses/by/4.0), which
permits unrestricted use, distribution, and reproduction in any
medium, provided the original work is properly cited.
