https://doi.org/10.1140/epjd/e2012-30180-7
Regular Article
Double strand breaks in DNA resulting from double ionization events
1
Department of Physics, Oakland University,
Rochester, Michigan
48309,
USA
2
Frankfurt Institute for Advanced Studies,
Ruth-Moufang-Str. 1,
60438
Frankfurt am Main,
Germany
3
On leave from A.F. Ioffe Physical Technical
Institute, 194021
St. Petersburg, Russian
Federation
a e-mail: surdutov@oakland.edu
Received:
16
March
2012
Received in final form:
18
May
2012
Published online:
16
August
2012
A mechanism of double strand breaking in DNA due to the action of two electrons is considered. These are the electrons produced in the vicinity of DNA molecules due to ionization of water molecules with a consecutive emission of two electrons, making such a mechanism possible. The transport of secondary electrons, including the additional electrons, is studied in relation to the assessment of radiation damage due to incident ions. This work is a stage in the inclusion of double ionization events into the multiscale approach to ion-beam cancer therapy.
Key words: Topical issue: Atomic Cluster Collisions. Guest editors: Andrey V. Solov’yov and Andrey V. Korol
© EDP Sciences, Società Italiana di Fisica and Springer-Verlag 2012
