Theoretical study of charge transfer dynamics in collisions of C6+ carbon ions with pyrimidine nucleobases
Laboratoire de Spectrométrie Ionique et Moléculaire, Université de Lyon (Lyon I), CNRS-UMR5579, 43 Bd. du 11 novembre 1918, 69622 Villeurbanne Cedex, France
Received: 10 January 2012
Received in final form: 30 March 2012
Published online: 10 July 2012
A theoretical approach of the charge transfer dynamics induced by collision of C6+ ions with biological targets has been performed in a wide collision energy range by means of ab-initio quantum chemistry molecular methods. The process has been investigated for the target series thymine, uracil and 5-halouracil corresponding to similar molecules with different substituent on carbon C5. Such a study may be related to hadrontherapy treatments by C6+carbon ions and may provide, in particular, information on the radio-sensitivity of the different bases with regard to ion-induced radiation damage. The results have been compared to a previous analysis concerning the collision of C4+ carbon ions with the same biomolecular targets and significant charge effects have been pointed out.
Key words: Topical issue: Atomic Cluster Collisions. Guest editors: Andrey V. Solov’yov and Andrey V. Korol
© EDP Sciences, Società Italiana di Fisica and Springer-Verlag 2012