https://doi.org/10.1007/s100530070098
Study of a X-ray laser-plasma source for radiobiological experiments: microdosimetry analysis and plasma characterisation
1
Dipartimento di Fisica "G. Occhialini”, Università degli Studi di Milano, Bicocca and
INFM UdR Milano Bicocca,
Via Emanueli 15, 20126 Milano, Italy
2
Max-Born-Institut für Nichtlineareoptik und Kurzzeitspektroscopie,
Max-Bornstr. 2a, 12489 Berlin-Adlershof, Germany
3
Dipartimento di Elettronica e Informazione, Politecnico di Milano, and INFM UdR Milano
Bicocca, 20126 Milano, Italy
4
Rutherford Appleton Laboratory, Chilton Didcot, Oxon, OX11 OQX, UK
Received:
16
September
1999
Revised:
1
February
2000
Published online: 15 August 2000
A soft X-ray laser-plasma source, used in radiobiology experiments with yeast cells, was characterised with flat crystal spectrometers and P-I-N diodes, obtaining an absolute measurement of the emission spectrum. A comparison with the results of simulations performed with the code RATION allowed the characterisation of the emitting plasma. A model for the energy deposition in yeast cells was developed to take into account the different cell structures (wall-membrane complex, cytoplasm and nucleus). Dose calculations performed considering the source emission spectrum were compared with direct measurements of transmission through plastic foils and allowed to verify the hypothesis of preferential dose deposition in the outer cellular regions.
PACS: 87.50.-a – Effects of radiation and external fields on biomolecules, cells and higher organisms / 42.55.-f – Lasers / 52.25.Nr – Emission, absorption, and scattering of X and γ radiation
© EDP Sciences, Società Italiana di Fisica, Springer-Verlag, 2000
